Methods and computer programs for predicting bilirubin levels in newborns

摘要

The present invention relates to a method and computer program for estimating bilirubin levels in a newborn, comprising the following steps: -Obtaining a series of bilirubin levels estimated at different time points from the newborn, -Acquiring a plurality of covariates from the newborn, each covariate containing information about the characteristics of the newborn, Providing a predefined bilirubin model function, wherein the bilirubin model function is configured to describe the time course of the bilirubin level of the newborn, Determining a number of model parameters of the bilirubin model function, wherein each model parameter is estimated from at least one covariate of a plurality of covariates and associated population model parameters, Determining from the bilirubin model function with the obtained set of bilirubin levels and the determined model parameters, the expected bilirubin level of the newborn during a time later than the last obtained bilirubin level of the series of bilirubin levels.