Vaccine composition for preventing swine mycoplasmal pneumonia and pleuropneumonia

摘要

The present invention relates to a multivalent vaccine composition capable of preventing the occurrence of pneumonia caused by porcine mycoplasma and pleural pneumococcus. The multivalent vaccine composition according to the present invention is Mycoplasma hyopneumoniae ( Mycoplasmahyopneumoniae , Mhp) and Mycoplasma hyopneumoniae attachment protein P97, Actinobacillosispleuropneumoniae (App) serotype 1, serotype 2, serotype 5 and secreted from each pleural pneumococcus By mixing toxins 1,2 and 3 (ApxI, Ⅱ and Ⅲ), simultaneous prevention of pneumonia by porcine mycoplasma and pleural pneumococcal bacteria is possible, and a superior protective effect can be obtained than a commercial vaccine. Furthermore, it has excellent initial defense ability, has no side effects after vaccination, and contains a recently popular serotype, which effectively reduces piglet mortality and prevents the deterioration of individuals due to chronic respiratory symptoms, which can be usefully used in the pig industry. have.