Method for evaluating human growth hormone deficiency by composition containing marshmorelin

摘要

The present invention relates to methods for measuring growth hormone levels in human or animal subjects, including methods for assessing pituitary-related growth hormone deficiency in human or animal subjects. The method comprises the steps of orally administering a composition containing marshmorelin to the subject, collecting 1, 2 or 3 post-dose samples from the subject within a range of 25 to 95 minutes after administration, 1 sample, 2 or And comparing growth hormone levels in the three samples to a single threshold. The method can be used to diagnose a pituitary-related growth hormone deficiency when all of the determined levels of growth hormone are below the single threshold.