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A sustained-release lipid pre-concentrate and a sustained-release injectable pharmaceutical composition in the form of lipid solution comprising the same
A sustained-release lipid pre-concentrate and a sustained-release injectable pharmaceutical composition in the form of lipid solution comprising the same
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机译:缓释脂质预浓缩物和包含其的脂质溶液形式的缓释注射药物组合物
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摘要
The present invention has 14 to 20 carbon atoms (C 14 to C 20 ) unsaturated fatty acids; Phospholipids; And a sustained-release lipid precursor formulation in the form of a lipid solution comprising α-tocopherol acetate, which does not contain diacyl glycerol and sorbitan unsaturated fatty acid ester; A precursor formulation that forms liquid crystals in an aqueous medium is provided. In addition, the present invention provides a pharmaceutical composition for sustained-release injection in the form of a lipid solution containing the precursor and a pharmacologically active substance, which does not contain diacyl glycerol and sorbitan unsaturated fatty acid ester.
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