首页> 外国专利> Benzyl-substituted, (pyridin-3-yl)methyl-substituted or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors

Benzyl-substituted, (pyridin-3-yl)methyl-substituted or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors

机译:苄基取代,(吡啶-3-基)甲基取代或(吡啶-4-基)甲基取代的恶二唑并吡啶衍生物作为生长素释放肽O-酰基转移酶(GOAT)抑制剂

摘要

The present invention relates to compounds of formula (I). [Formula I] In Formula I, Groups R 1 and R 2 are as defined in claim 1 and have valuable pharmacological properties, in particular, binding to ghrelin O-acyl transferase (GOAT) and modulating its activity. The compounds are suitable for the treatment and prevention of diseases that may be affected by the receptors, for example metabolic diseases, especially obesity.
机译:本发明涉及式(I)的化合物。 [式I]在式I中,基团R 1 和R 2 如权利要求1所定义,并且具有有价值的药理特性,特别是与生长素释放肽O-酰基转移酶结合(GOAT)并调节其活动。该化合物适用于治疗和预防可能受受体影响的疾病,例如代谢性疾病,特别是肥胖症。

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