Anti-MRSA composition comprising element from Sedum takesimense Nakai and beta-lactam antibiotics as active ingredient

摘要

The present invention relates to a composition for antimicrobial against methicillin-resistant Staphylococcus aureus (MRSA) containing a component derived from a serpentine plant and a beta-lactam-based antibiotic as an active ingredient, and specifically, a composition for antibacterial use of a serpentine plant extract, 1, One component selected from pharmaceutically acceptable salts of 2,4,6-tetra-O-galoyl-beta-glucose and 1,2,4,6-tetra-O-galoyl-beta-glucose; And beta-lactam antibiotic; relates to a composition for antibacterial against methicillin-resistant Staphylococcus aureus containing as an active ingredient. The composition of the present invention may exhibit excellent antibacterial activity against methicillin-resistant Staphylococcus aureus by containing the above two ingredients as active ingredients. In particular, due to the synergistic effect of the combination of the two ingredients, it can exhibit stronger antibacterial activity.Since the substance derived from the natural material, Sumirincho is used as an active ingredient, the amount of existing antibiotics can be reduced and replaced with a safer substance Therefore, it is expected to reduce the possibility of side effects caused by excessive use of existing antibiotics.