首页> 外国专利> Composition for preventing ameliorating or treating male infertility comprising extract of Prunus species as effective component

Composition for preventing ameliorating or treating male infertility comprising extract of Prunus species as effective component

机译：用于预防或改善男性不育的组合物，其包含李属提取物作为有效成分

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摘要

The present invention relates to a composition for preventing, ameliorating or treating male infertility, comprising Prunus japonica extract as an active ingredient. The extract may have an effect of increasing intracellular calcium and sperm motility, and may be usefully used in pharmaceutical compositions and health functional food compositions for preventing, improving or treating male infertility.

机译：本发明涉及一种用于预防，改善或治疗男性不育的组合物，该组合物包含李子提取物作为活性成分。该提取物可以具有增加细胞内钙和精子运动性的作用，并且可以有效地用于药物组合物和保健功能食品组合物中以预防，改善或治疗男性不育症。 展开▼

著录项

公开/公告号KR102066565B1

专利类型

公开/公告日2020-01-15

原文格式PDF

申请/专利权人 충남대학교 산학협력단;
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申请/专利号KR20170166734

发明设计人 이규필;
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申请日2017-12-06

分类号A61K36/73;A23L33/105;

国家 KR

入库时间 2022-08-21 11:05:35

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1. 包含混合草药提取物作为有效成分的用于预防和治疗男性不育症的组合物及其用途 [P] . 中国专利： CN106456691A . 2017-02-22

2. 包含罗汉果提取物作为有效成分的用于预防、改善或治疗呼吸系统疾病的组合物 [P] . 中国专利： CN112367859A . 2021-02-12

3. Composition for preventing ameliorating or treating male infertility comprising extract of Prunus species as effective component [P] . 韩国专利： KR20190066884A . 2019-06-14

机译：用于预防或改善男性不育的组合物，其包含李属提取物作为有效成分

4. Composition for preventing ameliorating or treating infertility caused by implantation failure comprising ginseng extract as effective component [P] . 韩国专利： KR20200041568A . 2020-04-22

机译：以人参提取物为有效成分的防止因植入失败而引起的不孕症的改善或治疗的组合物

5. Composition for preventing ameliorating or treating infertility caused by implantation failure comprising ginseng extract as effective component [P] . 韩国专利： KR102167989B1 . 2020-10-20

机译：以人参提取物为有效成分的防止因植入失败而引起的不孕症的改善或治疗的组合物

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10. Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Association of deletion allele of insertion/deletion polymorphism in alpha 2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus295Association of G1359A polymorphism of the endocannabinoid type 1 receptor (CNR1) with coronary artery disease (CAD) with type 2 diabetes mellitusCell growth, differentiation and stem cells - Vascular298Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus299Mesenchymal stromal-like cells (MLCs) derived from induced pluripotent stem (iPS) cells: a promising therapeutic option to promote neovascularization300Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease301Proinflammatory cytokine secretion and epigenetic modification in endothelial cells treated LPS-GinfivalisCell death and apoptosis - Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - Vascular320Effect of gastrin-releasing peptide (GRP) on vascular inflammationSignal transduction - Heart323A new synthetic peptide regulates hypertrophy in vitro through means of the inhibition of nfkb324Inducible fibroblast-specific knockout of p38 alpha map kinase is cardioprotective in a mouse model of isoproterenol-induced cardiac hypertrophy325Regulation of beta-adrenoceptor-evoked inotropic responses by inhibitory G protein, adenylyl cyclase isoforms 5 and 6 and phosphodiesterases326Binding to RGS3 and stimulation of M2 muscarinic acetylcholine receptors modulates the substrate specificity of p190RhoGAP in cardiac myocytes327Cardiac regulation of post-translational modifications, parylation and deacetylation in LMNA dilated cardiomyopathy mouse model328Beta-adrenergic regulation of the b56delta/pp2a holoenzyme in cardiac myocytes through b56delta phosphorylation at serine 573Nitric oxide and reactive oxygen species - Vascular331Oxidative stress-induced miR-200c disrupts the regulatory loop among SIRT1, FOXO1 and eNOS332Antioxidant therapy prevents oxidative stress-induced endothelial dysfunction and Enhances Wound Healing333Morphological and biochemical characterization of red blood cell in coronary artery diseaseCytoskeleton and mechanotransduction - 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V Garcia-Martinez, C Lopez Sanchez, W Hamed, 2016

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