PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OF PERIODONTAL LIGAMENT DISEASES COMPRISING SPIRULINA EXTRACT AS AN ACTIVE INGREDIENT

摘要

The present invention relates to a pharmaceutical composition for preventing or treating oral diseases containing spirulina extract as an active ingredient, wherein the spirulina extract induces differentiation from periodontal ligament stem cells to periodontal ligament cells and simultaneously promotes the formation of calcium nodules do. Therefore, the spirulina extract, spirulina extract treated periodontal ligament stem cells and periodontal ligament cells may be useful for the treatment of periodontal ligament disease or for strengthening the periodontal ligament as well as for immobilization of the implant.