- Antibiotic peptides targeting toxin-antitoxin system of Streptococcus pneumoniae and use thereof

摘要

The present invention relates to an antibiotic peptide targeting the toxin-antitoxin system of pneumococcus and uses thereof, and specifically, the antibiotic peptide of the present invention is to form a toxin-antitoxin complex of pneumococci without affecting the active site of the toxin. Inhibition, thereby inducing the death of pneumococcus by RNA decomposition activity of the isolated toxin, and also exhibits antibiotic activity against other bacteria, so it can be usefully used as an antibiotic composition.