首页> 外国专利> METHOD FOR PRODUCING AN EXOSOME THAT TRANSFERS A SUBSTANCE SPECIFICALLY TO TARGET AND EXOSOME PRODUCED BY THE SAME METHOD

METHOD FOR PRODUCING AN EXOSOME THAT TRANSFERS A SUBSTANCE SPECIFICALLY TO TARGET AND EXOSOME PRODUCED BY THE SAME METHOD

机译:产生一种物质的特定转移方法,该物质将特定物质转移到目标中并通过该方法产生

摘要

The present invention relates to a method for producing an exosome that delivers a target-specific substance and an exosome produced by the method. Specifically, an exosome prepared by introducing a vector in which a target peptide is inserted between the 170th and 171th amino acids of the CD9 protein of the present invention into an exosome-producing cell, the target peptide is expressed on the surface of the exosome, thereby exo By confirming that the drug trapped in the target is well delivered to the target tissue, the exosome can be usefully used as a target-specific transporter.
机译:本发明涉及递送靶标特异性物质的外泌体的制造方法以及通过该方法产生的外泌体。具体而言,将在本发明的CD9蛋白的第170个至第171个氨基酸之间插入有目标肽的载体导入到产生外泌体的细胞中而制备的外泌体,该目标肽在外泌体的表面表达,因此,exosome通过确认捕获在靶标中的药物可以很好地传递到靶标组织,可以有效地用作靶标特异性转运蛋白。

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