POLYMER HAVING MITOCHONDRIAL TARGETING ABILITY AND COMPOSITION FOR DRUG DELIVERY USING POLYMER

摘要

The present invention relates to a polymer having mitochondrial targeting ability and a composition for drug delivery using the polymer, wherein the polymer can form nanoparticles by self-assembly in a water phase even increasing a hydrophobic region of the polymer by synthesizing the polymer in which triphenylphosphonium is covalently attached to both ends of poly(-caprolactone) having multiple disulfide bonds or multiple diselenide bonds. In addition, the polymer can serve as a carrier which can deliver hydrophobic drugs into cells.;COPYRIGHT KIPO 2020