首页> 外国专利> Composition for protecting neuronal cells comprising naphthopyrone derivatives derived from the sprout of Cassia obtusifolia L.

Composition for protecting neuronal cells comprising naphthopyrone derivatives derived from the sprout of Cassia obtusifolia L.

机译:用于保护神经元细胞的组合物,其包含衍生自决明子的芽的萘并吡喃酮衍生物。

摘要

The present invention relates to a composition comprising a naphthopyrone derivative and a modified sprout extract containing it as an active ingredient. The composition according to an aspect of the present invention has an antioxidant effect and an effect of protecting nerve cells from oxidative stress or inhibiting apoptosis, and in particular, damage or death of retinal nerve cells or hippocampal nerve cells due to glutamate toxicity. It has an inhibitory effect, and treatment or prevention of visual acuity and deterioration and eye disease due to optic nerve damage, memory loss due to brain nerve damage, learning ability decline, depressive disorder occurrence and exacerbation, and pharmacy or food for the treatment or prevention of degenerative neurological disease It can be used as a composition.
机译:本发明涉及一种组合物,其包含萘并吡喃酮衍生物和含有其作为活性成分的改性的芽苗提取物。根据本发明一个方面的组合物具有抗氧化作用和保护神经细胞免于氧化应激或抑制细胞凋亡的作用,尤其是由于谷氨酸毒性而引起的视网膜神经细胞或海马神经细胞的损伤或死亡。它具有抑制作用,并且可以治疗或预防视神经损伤引起的视敏度和退化以及眼部疾病,脑神经损伤引起的记忆力丧失,学习能力下降,抑郁症的发生和恶化,以及用于治疗或治疗的药房或食品预防退行性神经系统疾病可用作组合物。

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