APPARATUS FOR HIGH THROUGHPUT CONTINUOUS DROPLET ELECTROPORATION FOR DELIVERY OF A MATERIAL AND A METHOD FOR DROPLET ELECTROPORATION USING THE SAME

摘要

Disclosed is a continuous process droplet electroporation device. The continuous process-type droplet electrochemical mill is provided in the form of a hollow cylinder, a first tubular electrode including a first inlet and a first outlet; An aqueous solution supply unit connected to the first tubular electrode and supplying an aqueous solution containing cells and a delivery material to the first tubular electrode to be discharged as droplets at a first outlet of the first tubular electrode; It is provided in the form of a hollow cylinder, includes a second inlet and a second outlet, is coaxial with the first tubular electrode, and the second inlet is the first outlet and the liquid of the first tubular electrode A second tubular electrode facing a part of the enemy spaced apart at a contactable distance; A power supply device that applies a voltage to the first tubular electrode and the second tubular electrode for electroporation of cells in the droplet; And a droplet suction part connected to the second tubular electrode and sucking the droplet into the second tubular electrode immediately after electroporation.