- Composition for Preventing and Treating Oral inflammatory disease Including Alginate-Antibiotic Composite and Method for Producing the Same

摘要

Disclosed is a composition for preventing and treating inflammatory diseases in the oral cavity comprising an alginate-antibiotic complex, and a method for manufacturing the same. The composition for the prevention and treatment of inflammatory diseases in the oral cavity according to an embodiment of the present invention is characterized in that it comprises an alginate-alginate-antibiotic complex formed by electrostatic crosslinking of the amine group contained in the antibiotic. In addition, the method for preparing a composition for preventing and treating inflammatory diseases in the oral cavity according to an embodiment of the present invention comprises the steps of preparing an aqueous alginate solution and an antibiotic solution containing a plurality of amine groups; A primary molding step of preparing an alginate-antibiotic hydrogel molded article comprising an alginate-antibiotic complex formed by electrostatic primary crosslinking between the alginate and the amine group included in the antibiotic; A washing step of washing the alginate-antibiotic hydrogel molding; And a secondary molding step of secondaryly molding the washed alginate-antibiotic hydrogel molding.