Method of differentiation of embryonic stem cell toward otic lineage using photobiomodulation

摘要

The present invention comprises (a) forming an embryoid body; And (b) collecting the embryos formed in step (a) and differentiating them into ear-associated tissues using photobioregulation during cultivation in ectodermal differentiation medium, ear linkage of embryonic stem cells using photobioregulation. It provides a method of differentiation into tissues. Since the embryonic stem cell differentiation method of the present invention can efficiently differentiate ESC into cells similar to inner ear hair cells, it can be usefully used as a method for differentiation into ear connective tissue in the field of stem cell differentiation.