CEACAM6 siRNA siRNA for inhibiting CEACAM6 expression and therapeutic agent for adenocarcinoma comprising thereof

摘要

The present invention relates to an siRNA delivery complex comprising siRNA and a pHLIP (low pH-induced transmembrane structure) for inhibiting CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) expression, the acidic microparticles using the siRNA delivery complex of the present invention Since it effectively suppresses CEACAM6 in tumor cells in the environment, it can be useful as a therapeutic agent for adenocarcinoma.