首页> 外国专利> Pharmaceutical composition and health functional food for preventing improving or treating inflammatory bowel disease including liposomes

Pharmaceutical composition and health functional food for preventing improving or treating inflammatory bowel disease including liposomes

机译:用于预防或治疗包括脂质体在内的炎症性肠病的药物组合物和保健功能食品

摘要

The present invention relates to a pharmaceutical composition and a health functional food for preventing, improving or treating an inflammatory bowel disease containing liposomes, and comprises krill oil interposed between phosphatidylcholine and the phosphatidylcholine, with respect to 23 to 32 parts by weight of the phosphatidylcholine. By containing liposomes containing 6 to 40 parts by weight of krill oil, it has anti-inflammatory and antioxidant effects, and even if it contains an active substance in the liposome, it has excellent storage stability, and the delivery of the active substance in the liposome to the inflammatory site in the intestine is very effective. It can be, even if the active substance in the lipid bilayer of the liposome is contained, the structure of the liposome remains stable for a long time, and even if the liposome is lyophilized, the anti-inflammatory and antioxidant effects are maintained, and the structural stability and storage stability of the active substance are not lowered, and the oral cavity It is possible to administer it, it is convenient to take, and it can be prevented, improved or treated with inflammatory bowel disease, and the pharmaceutical composition including the liposome of the present invention and the health functional food can prevent, improve or treat inflammatory bowel disease, The present invention relates to pharmaceutical compositions and health functional foods for preventing, improving or treating inflammatory bowel disease, including liposomes.
机译:本发明涉及用于预防,改善或治疗含有脂质体的炎性肠病的药物组合物和保健功能食品,相对于23〜32重量份的磷脂酰胆碱,在磷酰胆碱和磷脂酰胆碱之间含有磷虾油。通过包含含有6至40重量份的磷虾油的脂质体,它具有抗炎和抗氧化作用,即使它在脂质体中包含活性物质,也具有优异的储存稳定性,并且该活性物质在脂质体中的递送。脂质体对肠道的炎症部位非常有效。即使在脂质体的脂质双层中包含活性物质,也可以使脂质体的结构长时间保持稳定,并且即使将脂质体冻干,也可以维持抗炎和抗氧化作用,并且活性物质的结构稳定性和储存稳定性不会降低,并且可以口服,服用方便,并且可以预防,改善或治疗炎性肠病,所述药物组合物包括本发明的脂质体和健康功能食品可以预防,改善或治疗炎性肠病。本发明涉及用于预防,改善或治疗炎性肠疾病的药物组合物和健康功能食品,包括脂质体。

著录项

  • 公开/公告号KR102136627B1

    专利类型

  • 公开/公告日2020-07-22

    原文格式PDF

  • 申请/专利权人 세종대학교산학협력단;

    申请/专利号KR20180079467

  • 发明设计人 임수정;김진희;

    申请日2018-07-09

  • 分类号A61K9/127;A23L33;A61K31/685;A61K47/44;A61P1/04;

  • 国家 KR

  • 入库时间 2022-08-21 11:04:10

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