AR mTOR Nucleic acids for simultaneous inhibition of AR gene and mTOR gene

摘要

The present invention relates to a nucleic acid molecule that simultaneously suppresses the expression of the AR gene and the mTOR gene, and an anticancer pharmaceutical composition comprising the same, and specifically, in order to overcome the disadvantage of not having a high therapeutic effect due to the target specificity of siRNA, The double-stranded siRNA of the present invention, designed to simultaneously inhibit the expression of cancer-related AR gene and mTOR gene, promotes the death of cancer cells and has the effect of synergistically improving cancer cell death in combination treatment with anticancer agents. It can be usefully used as an anticancer composition or anticancer adjuvant.