首页> 外国专利> Freeze-dried formulation of exosomes derived from stem cell and anti-inflammatory composition comprising the same

Freeze-dried formulation of exosomes derived from stem cell and anti-inflammatory composition comprising the same

机译:来源于干细胞的外泌体的冻干制剂和包含其的抗炎组合物

摘要

The present invention provides a freeze-dried preparation of stem cell-derived exosomes used for preventing, suppressing, alleviating, improving or treating inflammation, and an anti-inflammatory composition comprising the same as an active ingredient. The freeze-dried preparation of stem cell-derived exosomes of the present invention or an anti-inflammatory composition containing the same as an active ingredient has excellent anti-inflammatory effect while stabilizing stem cell-derived exosomes, and in particular, stem cell-derived exosomes isolated and purified from stem cell culture medium Compared to this, it shows an excellent anti-inflammatory effect. Accordingly, the freeze-dried preparation of stem cell-derived exosomes of the present invention or an anti-inflammatory composition comprising the same as an active ingredient can be used to effectively prevent, inhibit, alleviate, improve or treat inflammatory reactions or inflammatory diseases.
机译:本发明提供了用于预防,抑制,减轻,改善或治疗炎症的干细胞来源的外泌体的冻干制剂,以及包含其作为活性成分的抗炎组合物。本发明的干细胞来源的外泌体的冷冻干燥制剂或包含其作为活性成分的抗炎组合物具有优异的抗炎作用,同时稳定了干细胞来源的外泌体,特别是干细胞来源的从干细胞培养基中分离纯化的外泌体与之相比,它具有出色的抗炎作用。因此,本发明的干细胞来源的外来体的冷冻干燥制剂或包含其作为活性成分的抗炎组合物可以用于有效地预防,抑制,减轻,改善或治疗炎性反应或炎性疾病。

著录项

  • 公开/公告号KR102148011B1

    专利类型

  • 公开/公告日2020-08-25

    原文格式PDF

  • 申请/专利权人 주식회사 엑소코바이오;

    申请/专利号KR20190034695

  • 发明设计人 이용원;조병성;김광일;

    申请日2019-03-26

  • 分类号A61K9/19;A61K35/12;A61K47/18;A61K47/22;A61K47/26;A61K8/02;A61K8/98;A61K9;A61K9/70;A61P17/10;A61Q19;

  • 国家 KR

  • 入库时间 2022-08-21 11:03:57

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