Method for Direct Conversion from Human Urine Cells into Nephron Progenitor Cells and Composition for Preventing or Treating Kidney Failure Comprising Induced Nephron Progenitor Cells Thereof

摘要

The present invention relates to a method for inducing direct dedifferentiation from urine cells to renal progenitor cells, and a pharmaceutical composition for preventing or treating kidney cell damage diseases comprising renal progenitor cells dedifferentiated by the method. The present invention enables mass production of personalized dedifferentiated kidney progenitor cells using urine cells, which are somatic cells that can be easily and repeatedly obtained without discomfort and pain, so that the field of incurable diseases and cell therapy that can be expanded to the fields of kidney damage healing and kidney regeneration It can be applied to the production of