ATR 2--6--N-5---3-15-A-3- 2-AMINO-6-FLUORO-N-5-FLUORO-PYRIDIN-3-YLPYRAZOLO15-APYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR ITS PREPARATION DIFFERENT SOLID FORMS AND RADIOLABELLED DERIVATIVES THEREOF

摘要

The present invention relates to compounds useful as inhibitors of ATR protein kinases. The present invention is a pharmaceutically acceptable composition comprising the compound of the present invention; Methods of treating a variety of diseases, disorders and conditions using the compounds of the present invention; A method for preparing the compound of the present invention; Intermediates for the preparation of the compounds of the present invention; And to the solid form of the compound of the present invention. The compounds of the present invention are of formulas I - A or IB. Formula IA Formula IB In formulas IA and IB above, the variables are as defined herein.