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Novel Bifidobacterium longum strain or Lactobacillus rhamnosus strain for preventing or treating obesity and the use thereof
Novel Bifidobacterium longum strain or Lactobacillus rhamnosus strain for preventing or treating obesity and the use thereof
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机译:用于预防或治疗肥胖的新型长双歧杆菌菌株或鼠李糖乳杆菌菌株及其用途
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摘要
The present invention relates to a novel Bifidobacterium longum strain or Lactobacillus rhamnosus strain having a prophylactic or therapeutic effect of obesity, and to a use thereof, the lactic acid bacterium Bifidobacterium longum of the present invention, and Lactobacillus rhamnosus ( Lactobacillus rhamnosus ) The treatment of each strain caused brown localization of white adipocytes, and in particular, it was confirmed that the expression of genes specific to beige adipocytes and brown adipocytes was significantly increased compared to the untreated control. In addition, as a result of the experiments of obese mice fed on a high fat diet, each strain showed a remarkable effect of suppressing weight gain compared to the negative control group, and the effect of increasing the expression of fever-specific genes in white adipose cells of the mice was confirmed. Therefore, each of the Lactobacillus Bifidobacterium longum strain and Lactobacillus rhamnosus strain exhibits an anti-obesity effect, so it can be usefully used as a food, medicine or feed for the prevention or treatment of obesity, which is very useful in related industries.
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