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Human antibody, L-4 receptor with high affinity
Human antibody, L-4 receptor with high affinity
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机译:人抗体,L-4受体,具有高亲和力
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摘要
FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to biotechnology and immunology. What is described is a recovered human antibody or its antigen-binding fragment. The antibody binds to human interleukin-4 alpha-receptor (hlL-4R). There are also described a nucleic acid molecule coding this antibody, an expression vector, a host cell, a method for producing such antibody and a therapeutic composition containing this antibody.;EFFECT: presented group of inventions can be used in medicine for treating asthma and atopic dermatitis.;15 cl, 3 tbl, 3 ex
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机译:领域:医药,药物。物质:发明涉及生物技术和免疫学。描述了一种回收的人抗体或其抗原结合片段。该抗体与人白介素4α受体(hlL-4R)结合。还描述了编码该抗体的核酸分子,表达载体,宿主细胞,产生该抗体的方法和包含该抗体的治疗组合物。效果:提出的一组发明可用于治疗哮喘和哮喘的药物。特应性皮炎。; 15 cl,3 tbl,3 ex
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