首页> 外国专利> ACCELERATOR FOR PRODUCING CATECHOLAMINE AND THERAPEUTIC AND PREVENTIVE AGENT AND THERAPEUTIC AND PREVENTIVE FOOD COMPOSITION FOR DISEASES CAUSED BY CATECHOLAMINE DEFICIENCY

ACCELERATOR FOR PRODUCING CATECHOLAMINE AND THERAPEUTIC AND PREVENTIVE AGENT AND THERAPEUTIC AND PREVENTIVE FOOD COMPOSITION FOR DISEASES CAUSED BY CATECHOLAMINE DEFICIENCY

机译:生产儿茶酚胺和治疗预防剂以及儿茶酚胺缺乏症所致疾病的治疗和预防食品成分的促进剂

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: group of invention refers to pharmaceutical industry, namely to a method for preparing an agent for treating or preventing Alzheimer's disease. Method of producing an agent for treating or preventing Alzheimer's disease, wherein said agent contains an earthworm extract extracted with water or aqueous ethanol, and/or dry powder of said extract, wherein said method comprises the following steps of preparing the extract: bringing live worm earthworm into contact with a chloride of at least one metal selected from a group consisting of potassium, sodium, magnesium and calcium; further bringing live worm into contact with powdered form of hydroxycarboxylic acid, diluted with water to bring pH from 2 to 5, and maintaining the obtained dilution for 3 to 180 minutes, or immersing and holding the live earthworm for 3 to 180 minutes in an aqueous solution of hydroxycarboxylic acid, having a pH value of from 2 to 5, washing the living earthworm with water, grinding the live earthworm and then lyophilisation of the obtained milled product; heating the lyophilized ground product at temperature of 110 °C or higher but lower than 130 °C, and dissolving said thermally treated product in water or in aqueous ethanol solution with ethanol concentration of 70 % or lower and then removing or separating insoluble fractions, where earthworm is red earthworm Lumbricus rubellus. Agent for treating or preventing Alzheimer's disease. Earthworm extract for stimulating catecholamine production. Use of an earthworm extract for treating Alzheimer's disease. Method of treating or preventing Alzheimer's disease.;EFFECT: above described solutions enable prevention and treatment of diseases caused by catecholamine deficiency.;5 cl, 4 dwg
机译:领域:医学;药物:发明组是指制药工业,即一种制备用于治疗或预防阿尔茨海默氏病的药剂的方法。生产用于治疗或预防阿尔茨海默氏病的试剂的方法,其中所述试剂包含用水或乙醇水溶液提取的worm提取物和/或所述提取物的干粉,其中所述方法包括以下制备提取物的步骤:携带活蠕虫worm与选自钾,钠,镁和钙中的至少一种金属的氯化物接触;使蠕虫与羟基羧酸粉末状粉末接触,用水稀释使pH为2至5,并将所得稀释液保持3至180分钟,或将蠕虫浸入并保持在水中3至180分钟pH值为2至5的羟基羧酸溶液,用水洗涤该活,,研磨该活worm,然后将得到的研磨产物冻干。将冷冻干燥的地面产品在110°C或更高但低于130°C的温度下加热,然后将所述热处理过的产品溶于乙醇浓度为70%或更低的水或乙醇水溶液中,然后除去或分离不溶性馏分is是红色earthLumbricus rubellus。治疗或预防阿尔茨海默氏病的药物。 extract提取物,用于刺激儿茶酚胺的产生。 extract提取物用于治疗阿尔茨海默氏病的用途。治疗或预防阿尔茨海默氏病的方法;效果:上述解决方案能够预防和治疗儿茶酚胺缺乏引起的疾病; 5 cl,4 dwg

著录项

  • 公开/公告号RU2708673C2

    专利类型

  • 公开/公告日2019-12-11

    原文格式PDF

  • 申请/专利权人 VELL STOUN KO.;

    申请/专利号RU20160133264

  • 申请日2015-01-13

  • 分类号A61K35/62;A61K35/56;A61P25;A61K9/14;B01D11/02;

  • 国家 RU

  • 入库时间 2022-08-21 11:02:47

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