首页> 外国专利> DIAGNOSTIC TECHNIQUE FOR METABOLIC SYNDROME IN SCHIZOPHRENIC PATIENTS RECEIVING NEUROLEPTIC THERAPY

DIAGNOSTIC TECHNIQUE FOR METABOLIC SYNDROME IN SCHIZOPHRENIC PATIENTS RECEIVING NEUROLEPTIC THERAPY

机译:精神分裂症患者接受神经脂疗法的代谢综合征的诊断技术

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to psychiatry. Presence of abdominal obesity - waist circumference (WC) more than 80 cm in females and more than 94 cm in males, blood pressure (BP) 130/85 mm Hg and more, concentration of triglycerides (TG) more than 1.7 mmol/l, concentration of high-density lipoprotein cholesterol (HDL-C) less than 1.03 mmol/l in males and less than 1.29 mmol/l in females, glucose concentration in blood plasma of 5.6 mmol/l and more. Additionally, concentrations of apolipoprotein C2 (AroC2) and apolipoprotein C3 (AroC3) are determined. If AroC2 concentration is more than 25 mcg/dl and AroC3 is more than 45 mcg / dl, metabolic syndrome is diagnosed. Method provides higher diagnostic accuracy of metabolic syndrome in patients with schizophrenia receiving neuroleptic therapy by determining WC, BP, TG, HDL-C and glucose in patients with schizophrenia and additional determination of AroC2 and AroC3 in the patients upon admission to the clinic.;EFFECT: invention can be used for diagnosing metabolic syndrome in schizophrenic patients receiving neuroleptic therapy.;1 cl, 1 tbl, 1 ex
机译:技术领域本发明涉及医学,即精神病学。腹部肥胖-女性腰围(WC)大于80厘米,男性腰围(WC)大于94厘米,血压(BP)大于130/85毫米汞柱,甘油三酸酯(TG)浓度大于1.7 mmol / l,男性中高密度脂蛋白胆固醇(HDL-C)的浓度小于1.03 mmol / l,女性中小于1.29 mmol / l,血浆中的葡萄糖浓度为5.6 mmol / l以上。另外,确定载脂蛋白C2(AroC2)和载脂蛋白C3(AroC3)的浓度。如果AroC2浓度大于25 mcg / dl,而AroC3大于45 mcg / dl,则诊断为代谢综合征。该方法可通过测定精神分裂症患者的WC,BP,TG,HDL-C和葡萄糖,并在入院后进一步测定患者的AroC2和AroC3,从而提供接受精神抑制药治疗的精神分裂症患者代谢综合征的更高诊断准确性。 :本发明可用于接受精神抑制药治疗的精神分裂症患者的代谢综合征的诊断。; 1 cl,1 tbl,1 ex

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