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TREATMENT OF HEPATIC ADIPOSITIS WITH APPLICATION OF GLUCOCORTICOID AND MINERALOCORTICOID RECEPTOR ANTAGONISTS
TREATMENT OF HEPATIC ADIPOSITIS WITH APPLICATION OF GLUCOCORTICOID AND MINERALOCORTICOID RECEPTOR ANTAGONISTS
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机译:应用糖皮质激素和糖皮质激素受体拮抗剂治疗肝脂肪变性
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摘要
FIELD: medicine.;SUBSTANCE: invention refers to medicine and concerns treating fatty liver disease. For this purpose, a subject in need thereof is administered a therapeutically effective amount of a glucocorticoid receptor and mineralocorticoid receptor antagonist compound such as (E)-6-(4-phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione or 6-((1r,4r)-4-phenyl-cyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidine-2,4(1H, 3H)-dione.;EFFECT: invention provides treating fatty liver disease.;12 cl, 4 dwg, 5 ex
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机译:领域:药物;发明领域:本发明涉及药物并且涉及治疗脂肪肝疾病。为此目的,向有需要的受试者施用治疗有效量的糖皮质激素受体和盐皮质激素受体拮抗剂化合物,例如(E)-6-(4-苯基环己基)-5-(3-三氟甲基苄基)-1H-嘧啶- 2,4-二酮或6-(((1r,4r)-4-苯基-环己基)-5-(3-(三氟甲基)苄基)嘧啶-2,4(1H,3H)-二酮。治疗脂肪肝疾病。; 12 cl,4 dwg,5 ex
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