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METHOD OF PRODUCING MICELLAR COMPLEXES OF COPPER (II) USING NON-IONIC SURFACTANTS

机译:用非离子表面活性剂生产铜的微细络合物的方法

摘要

FIELD: cosmetic industry.;SUBSTANCE: invention relates to colloidal systems and solutions. Micellar complexes obtained using the disclosed method can be used in the formula of cosmetic preventive agents having fungicidal and antiseptic action, in preparation of compositions with fungicidal and antiseptic action for application in medicine, veterinary science and construction. Method of obtaining micellar complexes based on copper (II) cations stable in aqueous solutions involves continuous stirring at room temperature of a surfactant of decyl glucoside with bidistilled water until a transparent solution is formed, in which copper acetate is added as a biologically active agent, wherein the solution assumes a blue colour, then a non-ionic surfactant Tween-80 is successively added to the obtained solution as a stabilizer and bidistilled water in following ratio of components: 2 % decyl glucoside, 4 % Tween-80, 0.1 % copper acetate and bidistilled water, wherein the solution becomes colorless, thereafter, the vessel with solution is placed in a dark place for at least one day to obtain a solution with copper (II) complexes in a two-layer micellar shell.;EFFECT: obtained micellar complexes exhibit high biological activity compared to non-micellized forms of copper and stability of not less than a year during storage in a dark place and at least half a year during storage in light.;1 cl, 3 tbl
机译:技术领域本发明涉及胶体系统和溶液。使用所公开的方法获得的胶束复合物可以用于具有杀真菌和杀菌作用的化妆品预防剂的配方中,用于制备具有杀真菌和杀菌作用的组合物,以用于医学,兽医学和建筑领域。获得基于在水溶液中稳定的铜(II)阳离子的胶束配合物的方法,包括在室温下将癸基葡糖苷表面活性剂与双蒸馏水连续搅拌直至形成透明溶液,其中添加乙酸铜作为生物活性剂,其中溶液呈蓝色,然后将非离子表面活性剂Tween-80作为稳定剂和双蒸馏水按以下组分比例依次添加到获得的溶液中:2%癸基葡糖苷,4%Tween-80、0.1%铜醋酸盐和双蒸馏水,溶液变为无色,此后,将装有溶液的容器在暗处放置至少一天,以在两层胶束壳中获得含铜(II)配合物的溶液。与非微粉化形式的铜相比,胶束复合物具有较高的生物活性,在黑暗处和至少半年杜里储存期间的稳定性不低于一年ng储存于光线下;; 1 cl,3汤匙

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