ANTIRABIC INACTIVATED EMULSION CULTURE VACCINE FOR PROPHYLACTIC IMMUNIZATION OF DOMESTIC CARNIVORES AND FARM ANIMALS

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology, specifically to developing an antirabic inactivated emulsion culture vaccine for prophylactic immunization of domestic carnivores and farm animals. Vaccine contains avirulent and purified antigenic material from strain "VNIIZZh" of rabies virus, obtained in transplantable suspension cell line from newborn golden hamster kidney (BHK-21/SUSP/ARRIAH), which is a suspension, containing predominantly immunogenic components of a rabies virus (glycoprotein and nucleoprotein), an oil adjuvant Montanide ISA-61 VG, a preservative merthiolate in effective ratios.;EFFECT: vaccine has high immunogenicity and is capable of providing long-term and reliable protection against rabies virus of the genetic line RABV.;10 cl, 16 dwg, 12 tbl, 14 ex