首页> 外国专利> METHOD FOR PREDICTION OF RISK OF INTRAOPERATIVE ISCHEMIC VASCULAR COMPLICATIONS ACCOMPANYING CAROTID ENDARTERECTOMY

METHOD FOR PREDICTION OF RISK OF INTRAOPERATIVE ISCHEMIC VASCULAR COMPLICATIONS ACCOMPANYING CAROTID ENDARTERECTOMY

机译:预测术中缺血性血管并发症伴有颈动脉狭窄的风险的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to ultrasonic diagnostics in neurosurgery, and can be used for prediction of a risk of developing intraoperative, ischemic complications accompanying carotid endarterectomy. Anamnestic data of the patient are collected: history of hypertension (AH), myocardial infarction (MI). In the absence of hypertensive disease, the AH value "0" is assigned, in the presence of the hypertensive disease of 1st stage – "1", 2nd stage – "2", 3rd stage – "3". In the absence of myocardial infarction in the past medical history, the MI parameter is set to "0" if the myocardial infarction is older than 1 month – "1"; prescription of less than 1 month – "2". Carrying out US duplex scanning of carotid arteries with determining plaque thickness (D) in imaging corresponding to maximum plaque size, and ulceration depth (H) in an atherosclerotic plaque by the degree of the plaque surface contrast defect in the color Doppler mapping (CDM) mapping mode. If ulceration depth H1/3D is detected, this parameter (H;D) is assigned the value "0", if observing 1/3D≤H2/3D, assigning the value "1", if observing a pitting depth H≥2/3D, assigning this parameter the value "2". Contrasted intensified US carotid artery scanning is performed, wherein area of plaques contrast (C) is determined relative to total surface area of plaques (F) in imaging corresponding to maximum size of plaques. When obtaining C1/3F, setting said parameter (C;F) to "0"; at 1/3F≤C1/2F – value "1"; at C≥1/2F is a value of "2". It is followed by bilateral Doppler monitoring of cerebral blood flow with detection of microembolic signals (MES) in cerebral vessels, wherein the number of detected microparticles (S) is determined during the observation hour. If no microparticles are detected, this parameter S is assigned "0", if microparticles are detected, a value corresponding to the number of microparticles is assigned to this parameter. Risk (R) of developing intraoperative ischemic vascular complications is determined by formula R = 27.9 *(AH) + 14.6 * (MI) + 14.9 *(H;D) + 6.5 * (S) + 24.8 * (C;F) – 4.3. When obtaining value R≥24.6 conclude a high risk of developing intraoperative ischemic vascular complications. If R24.6 is obtained, a low risk of developing intraoperative ischemic vascular complications.;EFFECT: method provides determining the risk of developing ischemic stroke during carotid endarterectomy by calculating a risk of developing ischemic stroke during carotid endarterectomy.;1 cl, 3 dwg, 7 tbl, 2 ex
机译:技术领域本发明涉及医学,即神经外科中的超声诊断,并且可以用于预测伴随颈动脉内膜切除术的术中缺血性并发症发生的风险。收集患者的回忆数据:高血压病史(AH),心肌梗塞(MI)。在没有高血压疾病的情况下,在第一阶段为“ 1”,第二阶段为“ 2”,第三阶段为“ 3”的高血压疾病的情况下,将AH值指定为“ 0”。在过去的病史中没有心肌梗塞的情况下,如果心肌梗塞大于1个月,则将MI参数设置为“ 1”;否则,将MI参数设置为“ 0”。处方少于1个月-“ 2”。通过彩色多普勒定位(CDM)中斑块表面对比度缺陷的程度,对美国颈动脉进行双工扫描,确定成像中相应于最大斑块大小的斑块厚度(D)和动脉粥样硬化斑块的溃疡深度(H)映射模式。如果检测到溃疡深度H <1 / 3D,则如果观察到1 /3D≤H<2 / 3D,则为该参数(H; D)分配值“ 0”;如果观察到点蚀深度,则将值分配为“ 1” H≥2/ 3D,为此参数分配值“ 2”。进行对比增强的美国颈动脉扫描,其中相对于斑块的最大尺寸,在成像中相对于斑块的总表面积(F)确定斑块的对比度(C)。当获得C <1 / 3F时,将所述参数(C; F)设置为“ 0”。在1 /3F≤C<1 / 2F时–值为“ 1”; C≥1/ 2F时的值为“ 2”。接下来是对脑血流进行双边多普勒监测,并检测脑血管中的微栓塞信号(MES),其中在观察小时内确定检测到的微粒(S)的数量。如果未检测到微粒,则将该参数S指定为“ 0”,如果检测到微粒,则将与微粒数对应的值分配给该参数。发生术中缺血性血管并发症的风险(R)由公式R = 27.9 *(AH)+ 14.6 *(MI)+ 14.9 *(H; D)+ 6.5 *(S)+ 24.8 *(C; F)–确定4.3。当获得R≥24.6的值时,得出发生术中局部缺血性血管并发症的高风险。如果获得R <24.6,则发生术中局部缺血性血管并发症的风险较低;效果:该方法可通过计算在颈动脉内膜切除术期间发生缺血性卒中的风险来确定发生颈动脉内膜切除术期间发生缺血性中风的风险。; 1 cl,3 dwg ,7汤匙,2前

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