VARIABLE DOMAINS OF LIGHT AND HEAVY CHAINS OF MURINE MONOCLONAL ANTIBODIES AGAINST HUMAN ALPHA-DEFENSINS 1-3 (HNP 1-3), ANTIGEN-BINDING FRAGMENTS (FAB) AGAINST HUMAN HNP 1-3, CONTAINING SAID DOMAINS

摘要

FIELD: biotechnology.;SUBSTANCE: present invention relates to biotechnology and immunology. Variable domains of heavy (VH) and light (VL) chains of mouse monoclonal antibodies against human alpha-defensins 1–3 (HNP 1–3), as well as an antigen-binding fragment of Fab, which selectively bind to alpha-defensins 1-3 (HNP 1–3) of a human being.;EFFECT: present invention can find further application in diagnosing intraarticular infection of large joints.;3 cl, 9 tbl, 5 ex, 9 dwg