METHOD FOR INITIATION OF TUMOR CELL DEATH BY 5-AMINOLEVULINIC AND SUCCINIC ACIDS AND HF- AND UHF-ENERGY OF WAVE RADIATION

摘要

FIELD: medicine; pharmaceuticals.;SUBSTANCE: invention relates to method of initiating tumor cell death, intended for treating cancer patients having tumor tissues with metastases, for their hyperthermia in all organs of human body HF- and UHF-energy, characterized by that before treatment, a person is transferred to a no-carbohydrate diet for 3 days to create glucose starvation and subsequent maximum saturation of oncological cells with electron-ion solutions of 5-aminolevulinic acid preparation "Alasens" with intravenous introduction in megadose 20–30 mg/kg of human body weight for 3–6 hours before physiotherapy and succinic acid in megadose 3000 mg per person, taken orally, 0.5–2.5 hours before physiotherapy, followed by selective hyperthermia of tumor tissues HF-energy in accordance with depth of their location and depth of electromagnetic wave penetration into human body of 1100 centimeters at the resolved frequency f=13.56 MHz with the total tumor tissue heating rate at that frequency of 0.072 °C/s for 193 s to the tumor tissue heating temperature of 50.5 °C, while heating healthy tissues not higher than 40 °C.;EFFECT: disclosed is a method for initiation of tumor cell death by 5-aminolevulinic and succinic acids and HF- and UHF-energy of wave radiation.;1 cl, 1 ex, 2 tbl