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METHOD FOR PREDICTION OF RISK OF SEVERE ADVERSE CARDIAC EVENTS
METHOD FOR PREDICTION OF RISK OF SEVERE ADVERSE CARDIAC EVENTS
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机译:预测严重不良心脏事件风险的方法
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摘要
FIELD: medicine.;SUBSTANCE: group of inventions relates to a method for prediction of the risk of a severe undesirable cardiac event or death in an individual, who suffers acute myocardial infarction (AMI), including determining the level of protachykinin or its fragments in body total body water and establishing a correlation of said level of protachykinin or fragments thereof with a risk of developing a severe undesired cardiac event or death. Group of inventions also relates to the use of a binding molecule which binds protachykinin or fragments thereof with sequences selected from the group of SEQ ID NO: 2–12, in said method.;EFFECT: group of inventions provides a method for predicting a risk of a severe undesirable cardiac event or death in an individual suffering AMI.;23 cl, 2 ex, 7 dwg, 7 tbl
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机译:发明领域本发明涉及一种用于预测患有急性心肌梗塞(AMI)的个体中严重的不良心脏事件或死亡的风险的方法,包括确定体内快速激肽或其片段的水平。体内总水分,并确定所述前激肽释放酶或其片段的水平与发生严重的不良心脏事件或死亡的风险之间存在相关性。本发明组还涉及在所述方法中使用结合protachykinin或其片段与选自SEQ ID NO:2-12的序列的结合分子的作用。效果:本发明组提供了一种预测风险的方法急性心肌梗死的严重不良心脏事件或死亡的危险性; 23 cl,2 ex,7 dwg,7 tbl
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