METHOD FOR EVALUATING RECEPTIVITY OF ENDOMETRIUM IN SECRETORY PHASE IN WOMEN WITH PRIMARY INFERTILITY CAUSED BY ENDOMETRIAL HYPOPLASIA

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly to pathomorphology, obstetrics and gynecology. Disclosed is a method of assessing endometrial receptivity in a secretory phase of a cycle in females suffering a uterine infertility caused by endometrial hypoplasia, in which by immunohistochemical method, p53 and PTEN receptor expression is determined in glands and stroma, followed by calculating prognostic index (PI) by formula PI=X1×-0.69+0.59×X2+0.99×X3+0.37×X4-69.3. If PI is more than 0, a conclusion is made on the endometrium's readiness for successful implantation of the embryo and possibility of directing the woman into the high-tech reproductive technologies (HRT) program. If PI is less than 0, low endometrial receptiveness and high risk of reproductive failure in HRT programs in women with primary infertility caused by endometrial hypoplasia are predicted.;EFFECT: invention provides more effective prediction of reproductive failures in females with endometrial hypoplasia and uterine infertility.;1 cl, 1 tbl, 3 ex