METHOD OF MEASURING CONCENTRATION AND TEMPERATURE OF MAGNETIC NANOPARTICLES WITHIN LIVING BODY BY NUCLEAR MAGNETIC RESONANCE USING MAGNETIC RESONANCE TOMOGRAPHY

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medical equipment. According to tomogram obtained at induction B₁  (kT/P) (P is magnetic moment of nanoparticles, k is Boltzmann constant, T is thermodynamic temperature) for each section magnetization M₁ is determined, by tomogram obtained at induction B₂  (3kT/P), for each section magnetization M₂ is determined. According to magnetization M₁ there is local temperature of nanoparticles T = PB₁/kln(M₂/M₁), by magnetization M₂ there is local concentration of nanoparticles N = (M₂/P). Magnetizations M₁ and M₂ of tissue area are determined by shifts of its tomographic image with change of sign of pulse gradient of tomograph.;EFFECT: method of determining local concentrations and temperatures of magnetic nanoparticles within a living body, which can be used to control the process of nanoparticles transporting to body organs and heating nanoparticles for suppressing new growths by hyperthermia, consists in obtaining tomograms of selected tissue sections with two values of magnetic field induction of the tomograph.;1 cl