METHOD FOR DIFFERENTIAL DIAGNOSIS OF PERIPHERAL RETINAL HAEMANGIOBLASTOMA AND REACTIVE ASTROCYTIC RETINAL TUMOR

摘要

FIELD: medicine.;SUBSTANCE: invention relates to ophthalmology and is intended for differential diagnosis of peripheral retinal haemangioblastoma (RHB) and reactive astrocytic retinal tumor (RART). In the lachrymal fluid of the affected eye, the level of the macrophage inflammatory protein 1α is determined (MIP-1α). If its level is 17.1 pg/l and more, RART is diagnosed, RHB is diagnosed at less than 17.1 pg/ml.;EFFECT: method enables providing reliable, based on objective quantitative indicators, differential diagnosis of RHB and RART with higher diagnostic accuracy and selection of differentiated management approach to patients, their further monitoring, as well as examination for the purpose of detecting tumors of other localizations associated with VHL syndrome.;1 cl, 2 ex