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METHOD FOR PREDICTION OF UNFAVORABLE COURSE OF CHRONIC POST-TRAUMATIC UVEITIS AFTER SINGLE PENETRATING SURGICAL INTERVENTION ON EYEBALL

机译:眼球单次穿刺手术后预测慢性创伤后紫外线的不利过程的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to ophthalmology, and is intended for prediction of unfavourable course of chronic posttraumatic uveitis (CPTU) after single penetrating surgical intervention on an eyeball. That is ensured by determining an absolute number of CD3 + CD4 + T-helpers, CD19 + B-lymphocytes and a relative amount of NK cells CD16 + CD56 + after single penetrating surgical intervention on an eyeball in peripheral blood. If absolute number of T-help CD3 + CD4 + is less than 0.69 × 109 /l, and/or the absolute CD19 + B-lymphocyte count below 0.16 × 109 /l, and/or relative number of NK-cells CD16 + CD56 + more than 21.6 %, unfavourable course is predicted.;EFFECT: method enables detecting an unfavourable prognosis in the patients with long-term clinical course of CPTU after a single surgical intervention, timely selection of pathogenically oriented therapy and higher clinical effectiveness.;1 cl, 7 ex, 1 tbl
机译:技术领域本发明涉及医学,即眼科,旨在预测对眼球的单次穿透性外科手术后的慢性创伤后葡萄膜炎(CPTU)的不利病程。通过对外周血眼球进行单次穿刺手术后确定CD3 + CD4 + T辅助物,CD19 + B淋巴细胞的绝对数量和NK细胞CD16 + CD56 +的相对数量,可以确保这一点。如果T-help CD3 + CD4 +的绝对数量小于0.69×10 9 / l,和/或CD19 + B淋巴细胞的绝对数量低于0.16×10 9 / l,和/或NK细胞CD16 + CD56 +的相对数量超过21.6%,则预测病程不利;效果:该方法可在单次接受CPTU长期临床病程的患者中检测不良预后手术干预,及时选择以病原为导向的治疗方法,具有更高的临床疗效。; 1 cl,7 ex,1 tbl

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