Systems and methods for correcting red-eye artifacts in a target image of a subject. Images captured by a camera, including a raw image, are used to create the target image. An eye region of the target image is modulated to correct the red-eye artifacts, wherein the correction is performed based on information extracted from the raw image and / or the target image. Modulation involves recognizing landmarks associated with the eye area; Estimating the spectral response of the red-eye artifacts; Segmenting an image area of the eye based on the estimated spectral response of the red eye artifacts and the detected landmarks, forming a repair mask; and modifying an image area associated with the repair mask.
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