首页> 外国专利> Pharmaceutical composition for preventing or treating gestational trophoblastic disease comprising decanoic acid

Pharmaceutical composition for preventing or treating gestational trophoblastic disease comprising decanoic acid

机译:包含癸酸的用于预防或治疗妊娠滋养细胞疾病的药物组合物

摘要

The present invention relates to a composition comprising decanoic acid as an active ingredient, and more specifically, a pharmaceutical composition for preventing or treating gestational trophoblast disease comprising decanoic acid as an active ingredient and decanoic acid as an active ingredient The present invention relates to a health functional food composition for preventing or improving gestational trophoblast disease. The composition comprising decanoic acid according to the present invention as an active ingredient proliferates the trophoblast cells by inhibiting the phosphorylation of sub-transmitters that regulate PI3K/AKT and MAPK signaling mechanisms in trophoblast cells that penetrate into the endometrium of the mother in early pregnancy And as it has the effect of inhibiting the permeability and improving the cell death effect, it can be usefully used in fields related to pharmaceuticals and functional foods that can prevent and treat gestational trophoblastic diseases invented by abnormal development of trophoblast cells.
机译:本发明涉及一种以癸酸为有效成分的组合物,更具体地说,涉及一种以癸酸为有效成分,以癸酸为有效成分的预防或治疗妊娠滋养细胞疾病的药物组合物。用于预防或改善妊娠滋养细胞疾病的功能性食品组合物。根据本发明的包含癸酸作为活性成分的组合物通过抑制调节滋养层细胞的PI3K / AKT和MAPK信号传导机制的亚递质的磷酸化来增殖滋养层细胞,所述滋养层细胞在怀孕早期渗透到母亲的子宫内膜中,并且由于它具有抑制通透性和改善细胞死亡效果的作用,因此可以有效地用于与药物和功能性食品有关的领域,这些领域可以预防和治疗由滋养层细胞异常发育引起的妊娠滋养层疾病。

著录项

  • 公开/公告号KR1020200071384A

    专利类型

  • 公开/公告日2020-06-19

    原文格式PDF

  • 申请/专利权人 고려대학교 산학협력단;

    申请/专利号KR1020180159073

  • 发明设计人 송권화;임화선;양창원;

    申请日2018-12-11

  • 分类号

  • 国家 KR

  • 入库时间 2022-08-21 10:56:59

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