Plasmodium sporozoite NPDP peptide as vaccine and target, novel malaria vaccine, and antibody binding thereto

摘要

The invention provides a fragment of the periplasmic sporozoite protein represented by SEQ ID NO: 1 for use in, for example, a malaria vaccine. The present invention also relates to a nucleic acid encoding a fragment of the Plasmodium sporozoite-surrounding protein represented by SEQ ID NO:1, a composition comprising a fragment of the Plasmodium sporozoite-surrounding protein represented by SEQ ID NO:1, and SEQ ID NO:1. Antibodies that bind to fragments of the represented Plasmodium sporozoite periprotein are provided. The antibody according to the present invention is a P. It binds specifically to Falciparum sporozoites and can be used for the prevention and/or treatment of malaria. [Selection diagram] None