COMPOSITIONS DE FILM PHARMACEUTIQUE POUR L'ADMINISTRATION DE COMPOSÉS LIPOPHILES DANS ET/OU À TRAVERS LA PEAU

摘要

Pharmaceutical composition for delivery of lipophilic compounds into and/or across the skin, comprising: not less than 55% by weight of volatile solvent or a mixture of such solvents; at least one lipophilic compound; one or more phospholipids; one or more film-forming polymers; and an oily additive which is a rich-polyunsaturated fatty acids mixture, proportioned such that polyunsaturated fatty acids constitute the predominant component of said mixture based on the total of weight of fatty acids in the mixture, the polyunsaturated fatty acids include linoleic acid omega 6 and α-Linoleic acid omega 3 at weight ratio of not less than 2:1. The oil additive is preferably hemp seed oil.