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ÉVALUATION DE L'ÂGE GESTATIONNEL PAR MÉTHYLATION ET PROFILAGE DE TAILLE D'ADN PLASMATIQUE MATERNEL
ÉVALUATION DE L'ÂGE GESTATIONNEL PAR MÉTHYLATION ET PROFILAGE DE TAILLE D'ADN PLASMATIQUE MATERNEL
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摘要
Temporal variations in one or more characteristics measured from a cell-free DNA sample are used to estimate a gestational age of a fetus. Example characteristics include the methylation level measured from the cell-free DNA sample, size of DNA fragments measured from the cell-free DNA sample (e.g., proportion of fetal-derived DNA fragments longer than a specified size), and ending patterns of the DNA fragments align to a reference genome.
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