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PRODUCTION FERMENTATIVE DE L-MÉTHIONINE DÉPENDANT DE PROTÉINE COMPRENANT UN GROUPE THIOCARBOXYLE
PRODUCTION FERMENTATIVE DE L-MÉTHIONINE DÉPENDANT DE PROTÉINE COMPRENANT UN GROUPE THIOCARBOXYLE
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摘要
The present invention relates to a recombinant microorganism useful for the production of L-methionine and process for the preparation of L-methionine. The microorganism of the invention is modified in a way that the L-methionine production is improved by using a thiocarboxylated protein as sulfur donor and by expressing an enzyme having homoserine O-acetyltransferase activity without feedback inhibition by methionine and/or S-adenosylmethionine and an enzyme having O-acetylhomoserine sulfhydrylase activity.
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