首页>
外国专利>
COMPOSÉ AMINOMERCAPTAN, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION DANS LA PROTECTION CONTRE LE RAYONNEMENT
COMPOSÉ AMINOMERCAPTAN, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION DANS LA PROTECTION CONTRE LE RAYONNEMENT
展开▼
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention discloses an amino mercaptan compound, preparation method thereof and use thereof in radiation protection. The compound has the structure of formula I, wherein Ais selected from -C(O)NR-,-S(O)-NR-, -S(O)NRor -R-NR-; Ais selected from carbonyl, sulfonyl, sulfinyl, substituted or unsubstituted Calkyl; R, R, R, and Rmay be the same or different and are selected from: hydrogen, substituted or unsubstituted C-Calkyl or heteroalkyl; n is an integer from 0 to 20,000; Rand Rare independently selected from hydrogen, X, substituted or unsubstituted Calkyl; X is selected from F, Cl, Br or I; Ris selected from substituted or unsubstituted C-Calkyl; and Ris selected from hydrogen, substituted or unsubstituted C-Calkyl. The compound has the effects of reducing the biological damage caused by ionizing radiation, extending the survival period and survival rate of the radiated animals, and significantly alleviating the side effects of radiotherapy, and has a low toxicity. The present invention opens up a new way for protection and treatment of ionizing radiation damage.
展开▼