AGENTS CIBLANT LE FACTEUR DE VON WILLEBRAND (VWF) ET LEURS PROCÉDÉS D'UTILISATION

摘要

Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.