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一种治疗革兰氏阳性菌引起的感染的药物及其合成方法

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摘要

本发明公开了一种治疗革兰氏阳性菌引起的感染的药物及其合成方法，所述药物的化学结构为式（Ⅱ）。式（Ⅱ）可以作为治疗革兰氏阳性菌引起的感染的药物。特别是作为治疗MRSA引起的感染的药物，本发明丰富了抗革兰氏阳性菌药物治疗化合物库，对革兰氏阳性菌引起的感染的治疗起到积极地作用。

著录项

公开/公告号CN108690012A

专利类型发明专利
公开/公告日2018-10-23

原文格式PDF
申请/专利权人曹艳;
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申请/专利号CN201810313203.4
发明设计人曹艳;
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申请日2017-06-10
分类号
代理机构
代理人
地址 261053 山东省潍坊市奎文区玄武街与虞河路交叉口北行160米路东
入库时间 2023-06-19 06:52:36

法律信息

法律状态公告日

法律状态信息

法律状态
2020-05-22

发明专利申请公布后的视为撤回 IPC(主分类):C07D417/12 申请公布日:20181023 申请日:20170610

发明专利申请公布后的视为撤回
2018-11-16

实质审查的生效 IPC(主分类):C07D417/12 申请日:20170610

实质审查的生效
2018-10-23

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专利
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1. 一种治疗革兰氏阳性菌引起的感染的药物及其合成方法 [P] . 中国专利： CN108558854A . 2018-09-21
2. 一种TRPC1肽类分子在制备治疗病毒感染引起的炎症的药物中的应用 [P] . 中国专利： CN110664990B . 2021.03.16
3. PEPTIDE, PEGUILLED PEPTIDE, COMPOSITION, PHARMACEUTICAL COMPOSITION, BOTTLE, DISINFECTION SOLUTION, METHOD FOR GROWTH INHIBITION, REPLICATION OR INFECTIVITY OF A MICRO-ORGANISM, METHOD FOR INHIBITION OF A BACTERIAL GROWTH, BACTERIAL GROWTH INHIBITION, TREATMENT OF A MICRO-ORGANISM INFECTION IN A SUBJECT AND PREVENTION OF A DISEASE IN A SUBJECT CAUSED BY OR ASSOCIATED WITH A MICRO-ORGANISM INFECTION, METHOD FOR INHIBITING BACTERIAL GROWTH IN A SUBJECT, A METHOD OF TREATMENT OF A BACTERIAL TREATMENT SUBJECT AND TREATMENT OF A DISEASE CAUSED BY OR ASSOCIATED WITH A BACTERIAL INFECTION, METHOD FOR PREVENTING A DISEASE CAUSED BY OR ASSOCIATED WITH A BACTERIAL INFECTION IN A SUBJECT, METHOD FOR INHIBITION OF VIRAL REPLICATION IN A SUBJECT TO A SUBJECT TO A SUBJECT ON A SUBJECT AND TREATMENT OF A DISEASE CAUSED BY OR ASSOCIATED WITH A VIRAL INFECTION IN A SUBJECT, METHOD FOR THE PREVENTION OF A DISEASE CAUSED BY OR ASSOCIATED WITH A VIRAL INFECTION IN A SUBJECT, METHOD FOR DISINFECTING AN INA [P] . BR112017028190A2 . 2018-09-04

机译：肽，规定的肽，成分，药物成分，瓶，消毒溶液，微生物的生长抑制，复制或感染的方法，细菌生长的抑制方法，细菌生长的抑制作用，治疗由微生物感染引起或与之有关的疾病的预防，疾病的抑制方法，一种细菌治疗方法的治疗和一种或多种细菌引起的疾病的治疗感染，预防由细菌感染引起的疾病或与之相关的疾病的方法，在受试者体内抑制病毒复制的方法以及对由细菌引起或与之相关的疾病的治疗在主题中，一种预防由对象中的病毒感染引起或与之相关的疾病的方法，一种用于对INA进行消毒的方法
4. composition; pharmaceutical composition; combination therapy; medical apparatus; method for administering at least one glycylcycline and at least one heparin; method for the administration of glycylcycline and heparin; method of treating intraabdominal infections with complications (ciai) and cutaneous infections and complications of the cutaneous structure (csssi) caused by gram negative and gram positive pathogens, anaerobic and methicillin-resistant strains and those resistant to staphylococcus aureus ( mssa and mrsa); method of treating intraabdominal infections with complications (ciai) and infections of the cutaneous and complicating skin structure (csssi) caused by gram negative and gram positive pathogens, anaerobic and methicillin-resistant strains of staphylococcus aureus ( mssa and mrsa) in a patient in need; antibiotic administration method; article of manufacture; kit; use of a glycylcillin of formula I or a pharmaceutically acceptable salt thereof; use of a heparin or pha [P] . BRPI0611070A2 . 2010-08-03

机译：组成;药物组合物;联合疗法医疗器械至少一种缩水甘油环素和至少一种肝素的给药方法;甘氨酰环素和肝素的给药方法;治疗由革兰氏阴性和革兰氏阳性病原体，厌氧和耐甲氧西林的菌株以及对金黄色葡萄球菌有抵抗力的菌株（mssa和mrsa）引起的合并症（ciai）和腹腔内感染的并发症（ciai）和皮肤感染以及皮肤结构并发症（csssi）;革兰氏阴性和革兰氏阳性病原体，金黄色葡萄球菌厌氧和耐甲氧西林菌株（mssa和mrsa）引起的并发症（CIAI）和皮肤感染和皮肤复杂结构（CSSS）感染的腹腔内感染的治疗方法;抗生素给药方法;制品;套件式I的糖基西林或其药学上可接受的盐的用途;肝素或相的使用
5. Processes for treating or preventing infection caused by at least one virus of the flaviviridae and diseases associated with said infection and infection caused by at least one virus of the genus hepacivirus of flavivirity and diseases associated with said infection, pharmaceutical composition to treat or prevent viral infections , it's composed [P] . BR9913157A . 2001-05-15

机译：治疗或预防由至少一种黄病毒科病毒引起的感染和与所述感染相关的疾病的方法以及由至少一种黄病毒属肝炎病毒属病毒引起的感染和与所述感染相关的疾病，用于治疗或预防病毒感染的药物组合物，它组成