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Can Streamlined Multicriteria Decision Analysis Be Used to Implement Shared Decision Making for Colorectal Cancer Screening?

机译:可以使用简化的多标准决策分析来实施大肠癌筛查的共享决策吗?

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摘要

BACKGROUND: Current US colorectal cancer screening guidelines that call for shared decision making regarding the choice among several recommended screening options are difficult to implement. Multicriteria decision analysis (MCDA) is an established method well suited for supporting shared decision making. Our study goal was to determine whether a streamlined form of MCDA using rank-order-based judgments can accurately assess patients' colorectal cancer screening priorities.METHODS: We converted priorities for 4 decision criteria and 3 subcriteria regarding colorectal cancer screening obtained from 484 average-risk patients using the analytic hierarchy process (AHP) in a prior study into rank-order-based priorities using rank order centroids. We compared the 2 sets of priorities using Spearman rank correlation and nonparametric Bland-Altman limits of agreement analysis. We assessed the differential impact of using the rank-order-based versus the AHP-based priorities on the results of a full MCDA comparing 3 currently recommended colorectal cancer screening strategies. Generalizability of the results was assessed using Monte Carlo simulation.RESULTS: Correlations between the 2 sets of priorities for the 7 criteria ranged from 0.55 to 0.92. The proportions of differences between rank-order-based and AHP-based priorities that were more than ±0.15 ranged from 1% to 16%. Differences in the full MCDA results were minimal, and the relative rankings of the 3 screening options were identical more than 88% of the time. The Monte Carlo simulation results were similar.CONCLUSIONS: Rank-order-based MCDA could be a simple, practical way to guide individual decisions and assess population decision priorities regarding colorectal cancer screening strategies. Additional research is warranted to further explore the use of these methods for promoting shared decision making.
机译:背景:目前的美国大肠癌筛查指南要求就几种推荐的筛查选项中的选择做出共同决策,这很难实施。多准则决策分析(MCDA)是一种非常适合支持共享决策的既定方法。我们的研究目标是使用基于等级的判断来确定简化的MCDA形式是否可以准确评估患者的结肠直肠癌筛查优先级。方法:我们将从484个平均值中获得的关于结肠直肠癌筛查的4个决策标准和3个子标准的优先级进行了转换,在先前的研究中,使用层次分析质心法将风险患者使用层次分析法(AHP)转换为基于等级的优先级。我们使用Spearman等级相关性和协议分析的非参数Bland-Altman限制比较了两组优先级。我们比较了目前推荐的三种结肠直肠癌筛查策略,评估了使用基于优先级排序和基于AHP的优先级对完整MCDA结果的不同影响。结果的通用性使用蒙特卡洛模拟进行评估。结果:7个标准的两组优先级之间的相关性介于0.55至0.92之间。基于等级顺序和基于AHP的优先级之间的差异比例大于±0.15,范围为1%至16%。完整MCDA结果的差异很小,并且三种筛选选项的相对排名在88%的时间内相同。结论:基于等级排序的MCDA可能是指导个人决策和评估大肠癌筛查策略人群决策优先级的简单实用方法。有必要进行更多的研究以进一步探索这些方法的使用,以促进共同的决策制定。

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