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Avaliação de técnicas de fisioterapia respiratória em modelo experimental de atelectasia em suínos recém-nascidos

机译:新生猪肺不张实验模型中呼吸理疗技术的评价

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摘要

Objective : To compare the effectiveness of two techniques of respiratory therapy in an experimental model of atelectasis by bronchial obstruction in newborn pigs. Methods : 24 pigs were analgesiados, sedated, tracheostomized and mechanically ventilated. For the induction of atelectasis, artificial mucus was infused (ethylene oxide, Sigma-Aldrich ™, USA) using an infusion pump through the tracheal tube with the pigs in the lateral position and inclined to the 30th. Confirmation of atelectasis was a chest X-ray or by a pressure drop of oxygen in arterial blood. After the animals were divided into 3 groups: group 1 that received tracheal aspiration after 20 minutes of confirmation of atelectasis, group 2 underwent the technique of bag squeezing over tracheal aspiration and group 3 received vibration chest. To evaluate the effectiveness of techniques one second X-ray was done. To evaluate the changes during the procedures were performed arterial blood gases and pulmonary mechanics evaluation pneumotachograph before and after the induction of atelectasis immediately and 30 minutes after the procedure. Results : The mean percentage change in the PO2 was statistically detect significant between the groups (control: 97,80±37,33, bag squeezing: 166,75±68,63 e vibration: 104,41±45,45, p=0,0408), with improvement in oxygenation in the group undergoing the technique of squeezing bag. The remaining variables did not differ. Conclusions : the results suggest that the technique of squeezing bag is more efficient than manual vibration, but clinical improvement was not accompanied by detectable radiological improvement.
机译:目的:比较两种呼吸疗法在新生猪支气管阻塞性肺不张实验模型中的有效性。方法:对24头猪进行镇痛,镇静,气管切开和机械通气。为了诱发肺不张,使用输液泵通过气管管注入人工粘液(环氧乙烷,Sigma-Aldrich™,美国),使猪侧卧并倾斜至第30位。肺不张的确诊是胸部X光检查或动脉血中的氧气压降。将动物分为三组后:第1组在确认不张20分钟后接受气管抽吸,第2组接受气囊挤压气管抽吸术,第3组接受振动胸。为了评估技术的有效性,完成了一秒钟的X射线检查。为了评估手术过程中的变化,在手术前后立即和手术后30分钟进行动脉血气和肺力学评估呼吸描记器。结果:两组间PO2的平均百分比变化在统计学上具有显着性意义(对照组:97,80±37,33,袋挤压:166,75±68,63 e振动:104,41±45,45,p = (0,0408),而采用挤压袋技术的组中的氧合作用得到改善。其余变量没有不同。结论:结果表明,挤压袋技术比手动振动更为有效,但临床改善并未伴随可检测的放射学改善。

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    Padoin Priscila Gularte;

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  • 年度 2012
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  • 原文格式 PDF
  • 正文语种 Português
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