Fluid structure interaction simulation of left ventricular flow dynamics under left ventricular assist device support

摘要

For patient’s receiving mechanical circulatoryudsupport, malfunction of the left ventricular assist deviceud(LVADs) as well as mal-positioning of the cannula imposesudserious threats to their life. It is therefore important toudcharacterize the flow pattern and pressure distribution withinudthe ventricle in the presence of an LVAD. In this paper, weudpresent a 2D axisymmetric fluid structure interaction modeludof the passive left ventricle (LV) incorporating an LVADudcannula to simulate the effect of the LVAD cannulaudplacement on the vortex dynamics. Results showed that largerudrecirculation area was formed at the cannula tip withudincreasing cannula insertion depth, and this is believed toudreduce the risk of thrombus formation. Furthermore, we alsoudsimulated suction events (collapse of the LV) by closing theudinlet. Vortex patterns were significantly altered under thisudcondition, and the greatest LV wall displacement wasudobserved at the part of the myocardium closest to the cannulaudtip