Appendicectomy using the tie-and-drop and purse-string technique without ligation of appendicular stump: a comparative study in rabbits

摘要

BACKGROUND: The purpose of this study was to compare two surgical techniques: tie and drop(A) and purse string without ligation of apendicular stump.(B) METHOD: The study included 36 young male New Zealand inbred rabbits, randomly distributed into two groups of 18, divided into three subgroups of six each, when eutanasia was done after postoperative periods of 7, 14, and 21 days. The animals were macroscopically evaluated according to the wound presence of abscess or dehiscense, and the abdominal cavity was evaluated according to the presence of peritoneal adhesions. Histological evaluation was conducted according to the following parameters: acute and chronic inflammatory infiltration, fibrosis, foreign-body granuloma, necrosis and mucosal layer integrity. RESULTS: No significants differences were found in the macroscopy studies in the postoperative periods of 7, 14 and 21 days, according to the wound presence of abscess or dehiscense; peritoneal adhesions presence were found in both techniques. As regards the histological findings in postoperative day 21, a difference on acute inflammatory infiltration, higher in group B, and the integrity of the mucosal layer, higher in group A were found. Counting of colagenous fibers in postoperative day 21 was significantly higher in group B. CONCLUSION: Regarding the histological findings, tie and drop technique is better than the purse string without ligation of apendicular stump.