Reaction of Some Beta-Diketones with Special Reference to Phenolic Compounds

摘要

1-(2-hydroxyphenyl)-3-(4-substituted phenyl)-propane-1,3-diones were prepared bythe Baker-Venkataraman reaction. 2-(2-hydroxyphenyl)-4-(4-substituted-phenyl-1, 5-benzodiazepines, 1-H-3-(2-hydroxyphenyl)-5-(4-substituted phenyl)-pyrazoles, and 1-phenyl-3-(2-hydroxyphenyl)-5-(4-substituted phenyl)-pyrazole derivatives were prepared starting from, phenolic beta-diketone and o-phenyl-enediamine, hydrazine, and phenyl hydrazine respectively. The products were characterized spectroscopically. All compounds were subjected to antifungal test against three fungi, Aspergillus, Fusarium and Rhizopus, and some of the compounds had shown antifungal activity against these fungi.